Overview
Khalid Saqr is computer-simulation engineer and researcher whose work follows a single difficult question across several fields: how does hidden structure become reliable evidence? The answer begins in heat, combustion and turbulent flow, becomes sharper in entropy and CFD model assessment, enters the living circulation through neurovascular haemodynamics, and later extends into knowledge capital, AI-mediated thought and market dynamics.
The centre of the current scientific record is the living artery. In 2026, Saqr described a transverse picoNewton-scale force in anisotropic Womersley flow1 and a resonant spectral cascade triggered by arterial geometry2. Together, those papers frame blood flow not simply as motion through a tube, but as organised mechanical information arriving at living tissue.
Early research
The earliest studies show a practical engineering discipline: make a system respond to changing conditions without losing useful energy. Bus air-conditioning work turned passenger comfort in hot, humid environments into a control problem71. Thermoelectric-generator studies asked whether exhaust heat could be recovered rather than discarded73, and early pipe-flow work treated heat transfer as a geometric problem inside moving fluid75.
That practical base quickly opened into computational vision. A Zanker plate study used CFD to read turbulence and swirl inside a flow-conditioning device76, while gas-turbine swirler work treated internal flow structure as the key to mixing and combustor performance77. The question that would remain with him was already visible: computation was not only a way to calculate a result; it was a way to see organisation that ordinary observation could miss.
Turbulent combustion work
Combustion made turbulence central. Spray-atomisation work examined how a continuous stream breaks into droplets19, while studies of non-premixed flames showed how incoming turbulence changes flame behaviour21. Work on soot and NOx then connected flame structure to consequence: the flow field does not merely burn fuel, it shapes what combustion leaves behind22.
The experimental side of this period mattered because it disciplined the models. Schlieren studies made confined explosions and combustion-kernel growth visible as optical events23. Pulse-detonation work connected transient mixing to measurable thrust29. In parallel, vortex-flame and combustor studies showed that rotation can organise mixing and instability rather than merely decorate a flow image33.
The same period also taught caution about computational authority. OpenFOAM implementation work tested whether combustion theory could survive as working software36, and radiation-model integration asked how far a simplified model could be trusted after validation38. By the end of the combustion apprenticeship, turbulence had become both a physical subject and a test of modelling judgement.
Design as diagnosis
The middle period is strongest when read not as a catalogue of applications, but as a diagnostic turn. Entropy-generation studies in swirling and pipe flows used simulation to locate where useful energy disappears49. Natural-convection work extended that diagnostic habit into heat-driven cavity flows50. In these papers, CFD was not only predicting performance; it was identifying the places where performance was being lost.
Renewable-energy and environmental-exposure studies took the same habit into harsher systems. Wells-turbine work read wave-energy conversion through viscous loss and entropy generation53. Wind-turbine studies first treated surface roughness as a force that deforms aerodynamic performance56, then extended the problem to dusty air and sandstorm exposure58. Marine-current turbine work moved the same question into water and angle of attack59; subsea-pipeline studies moved it into offshore loading and protection methods60.
This diagnostic view also had a public and infrastructural scale. Urban street-canyon studies connected geometry and wind to pollutant dispersion in public space47. Exergy work on a combined-cycle plant shifted attention from local flow to whole-plant efficiency63; a hydropower case study carried that concern into large infrastructure64. Across these studies, the recurrent question was not simply how a system works, but where its hidden losses, instabilities and environmental constraints become measurable.
Return to Egypt
Saqr received his Ph.D. from Universiti Teknologi Malaysia in 2011, months after the Egyptian revolution. When he returned to Egypt in 2012, the high-speed combustion problems on which he had trained no longer exhausted the meaning of his work. The move towards biofluid mechanics began gradually, through the same habits of modelling, instability analysis and evidence testing that had shaped the earlier engineering record.
The change was not a rejection of the earlier work. It was a change in what counted as the most consequential system. Machines, combustors and turbines had taught him how flow organises energy, loss and instability. Living vessels raised a harder question: how does a calculated vector field become useful knowledge about tissue, disease and medical decision-making?
Blood flow and the adequacy of models
Neurovascular haemodynamics turned CFD into an evidence problem. Doppler-based work on intracranial blood flow challenged the convenience of treating cerebral blood as a simple Newtonian engineering liquid12. Aneurysm studies then compared Newtonian, power-law and quasi-mechanistic viscosity models to ask how model choice changes interpretation13. In Moyamoya disease, exploratory CFD connected transient ischaemic attacks to haemodynamic complexity in diseased cerebral vessels17.
The decisive shift came when Saqr asked what the field had actually learned from its simulations. His critical review of intracranial aneurysm CFD placed the question at field level rather than case level18. The concern was no longer only whether one solver converged; it was how a scientific community decides that a model, measurement or image can count as evidence.
Blood flow is turbulent
The vascular work then sharpened around an anomaly: physiological blood flow may be turbulent. The 2020 Scientific Reports paper made that claim directly7. A later paper argued that vascular turbulence may not follow the classical Kolmogorov picture and may have mechanobiological significance8. In the carotid artery, work on stenosis and stenting showed that treatment can change near-wall turbulence, not only vessel geometry6.
At the same time, the wall itself became active. PIV experiments on idealised aneurysm models showed that wall compliance changes pulsatile flow behaviour3. Patient-specific aneurysm work connected wall elasticity to instability and wall shear stress4, while endothelial studies linked disturbed-flow characteristics to epigenetic response and mechano-miRNAs10. The boundary in the calculation had become a living surface.
Mechanobiology and the blood-cell signalling cascade
The 2026 Womersley-flow papers make this intellectual movement explicit. The artery is no longer presented as a passive conduit, and the wall is no longer just the place where a boundary condition is imposed. In anisotropic Womersley flow, Saqr identified a transverse force at a picoNewton scale relevant to cellular mechanics1. In arterial geometry, he then described a resonant spectral cascade that ties vessel shape to organised pulsatile motion2.
This is the most coherent scientific endpoint of the journey so far. Early work asked how engineered systems control heat and flow. Combustion work showed how turbulence organises instability. Entropy studies diagnosed loss. Vascular work made the boundary biological. The current question asks what signal, force or spectral structure living tissue actually receives from the moving blood beside it.
Tohoku University
The Tohoku University years placed Saqr's neurovascular work in a setting where engineering, medicine and technology assessment were closely connected. Studies of aneurysms18, Moyamoya disease17, physiological turbulence7 and wall compliance3 created expertise relevant to endovascular repair, clinical interpretation and the evidence standards surrounding medical technologies.
That expertise later connected him to MedTech venture diligence and expert-network work. In that setting, the familiar scientific question took an institutional form: not whether a technology sounds promising, but whether its evidence is strong enough to support development, capital and clinical translation. Work with Newchip Accelerator and later ScienceWerx extended the same evidence discipline into funding and private-sector judgement.
Knowledge capital, AI and financial markets
The later institutions and books are best read as an expansion of the same intellectual problem rather than a departure from science. A computational forensic study of Egyptian abortion rulings showed that hidden structure can also organise authority in legal language82. The Thomas Kuhn Foundation gives philosophical form to that concern with anomalies, evidence and scientific change.
KNOWDYN gives the same concern a practical form. Innovation Fast Forward argues for knowledge capital as something mined from human ingenuity and structured before it can be valued83. AllMind Society extends that question into collective intelligence and institutional research capacity85.
The most recent books widen the field while keeping the same centre. Self-debug Your Mind treats AI-assisted reflection as cognitive debugging rather than self-help84. Adjoint Thinking asks how people can think with language machines while preserving authorship, verification, originality and responsibility87. Kinetic Markets moves the vocabulary of constrained dynamics into finance, reading liquidity, volatility and risk as market mechanics rather than loose metaphor86.
Across these later works, the point is not to leave science for business or commentary. It is to carry the discipline of evidence into the systems that decide what knowledge becomes: ownership, judgement, investment, trust and institutional form.
Public record
The readable biography and machine-readable files describe the same public record. The biography gives the intellectual line of thought; the files give search engines, crawlers and AI systems the structured record.
References
- . A transverse picoNewton force revealed in anisotropic Womersley flow. Scientific Reports (2026). doi:10.1038/s41598-026-47474-x
- . Resonant spectral cascade in Womersley flow triggered by arterial geometry. Physics of Fluids (2026). doi:10.1063/5.0319995
- . Effects of wall compliance on multiharmonic pulsatile flow in idealized cerebral aneurysm models: comparative PIV experiments. Experiments in Fluids (2020). doi:10.1007/s00348-020-02998-4
- . Characteristic effect of wall elasticity on flow instability and wall shear stress of a full-scale, patient-specific aneurysm model in the middle cerebral artery: An experimental approach. Journal of Applied Physics (2022). doi:10.1063/5.0085417
- . Effects of wall compliance on pulsatile flow in a full-scale, patient-specific cerebral aneurysm model: Particle image velocimetry experiments. Medical Engineering and Physics (2025). doi:10.1016/j.medengphy.2025.104381
- . Non-Kolmogorov turbulence in carotid artery stenosis and the impact of carotid stenting on near-wall turbulence. AIP Advances (2022). doi:10.1063/5.0076271
- . Physiologic blood flow is turbulent. Scientific Reports (2020). doi:10.1038/s41598-020-72309-8
- . On non-Kolmogorov turbulence in blood flow and its possible role in mechanobiological stimulation. Scientific Reports (2022). doi:10.1038/s41598-022-16079-5
- . Numerical study on the energy cascade of pulsatile Newtonian and power-law flow models in an ICA bifurcation. PLoS ONE (2021). doi:10.1371/journal.pone.0245775
- . Epigenetic response of endothelial cells to different wall shear stress magnitudes: A report of new mechano-miRNAs. Journal of Cellular Physiology (2020). doi:10.1002/jcp.29436
- . Influence of bone marrow characteristic and trabecular bone morphology on bone remodelling process with FSI approach. Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications (2022). doi:10.1177/14644207221080115
- . Evidence for non-Newtonian behavior of intracranial blood flow from Doppler ultrasonography measurements. Medical and Biological Engineering and Computing (2019). doi:10.1007/s11517-018-1926-9
- . Computational fluid dynamics simulations of cerebral aneurysm using Newtonian, power-law and quasi-mechanistic blood viscosity models. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine (2020). doi:10.1177/0954411920917531
- . Investigation of newtonian and power-law blood flow models in a 180° curved pipe at low to medium shear rate. Journal of Advanced Research in Fluid Mechanics and Thermal Sciences (2020). doi:10.37934/ARFMTS.69.1.148162
- . Newtonian and non-newtonian CFD models of intracranial aneurysm: A review. CFD Letters (2020). record
- . Author Correction: The hemodynamic complexities underlying transient ischemic attacks in early-stage Moyamoya disease: an exploratory CFD study (Scientific Reports, (2020), 10, 1, (3700), 10.1038/s41598-020-60683-2). Scientific Reports (2020). doi:10.1038/s41598-020-62862-7
- . The hemodynamic complexities underlying transient ischemic attacks in early-stage Moyamoya disease: an exploratory CFD study. Scientific Reports (2020). doi:10.1038/s41598-020-60683-2
- . What does computational fluid dynamics tell us about intracranial aneurysms? A meta-analysis and critical review. Journal of Cerebral Blood Flow and Metabolism (2020). doi:10.1177/0271678X19854640
- . A mathematical model for predicting spray atomization characteristics in an Eulerian-Eulerian framework. International Communications in Heat and Mass Transfer (2010). doi:10.1016/j.icheatmasstransfer.2010.02.003
- . Numerical simulation of turbulent dispersion and atomization within sprays. Proceedings of the 2010 International Conference on Mechanical, Industrial, and Manufacturing Technologies, MIMT 2010 (2010). doi:10.1115/1.859544.paper79
- . Analyzing the effect of free stream turbulence on gaseous non-premixed flames. AIP Conference Proceedings (2010). doi:10.1063/1.3464941
- . Effect of free stream turbulence on NOx and soot formation in turbulent diffusion CH4-air flames. International Communications in Heat and Mass Transfer (2010). doi:10.1016/j.icheatmasstransfer.2010.02.008
- . Experiments on combustion kernel growth in gaseous explosions. AIP Conference Proceedings (2010). doi:10.1063/1.3464861
- . High-speed schlieren photography of confined gaseous explosions. International Journal of Mechanical and Materials Engineering (2010). record
- . Ideal detonation characteristics of biogashydrogen and -hydrogen peroxide mixtures. International Conference on Theoretical and Applied Mechanics, International Conference on Fluid Mechanics and Heat and Mass Transfer - Proceedings (2010). record
- . Theoretical notes on the mathematical modelling of gaseous detonations using boltzmann equation. Journal of Applied Sciences (2010). doi:10.3923/jas.2010.1476.1480
- . Single pulse detonation study of natural gas. International Conference on Theoretical and Applied Mechanics, International Conference on Fluid Mechanics and Heat and Mass Transfer - Proceedings (2010). record
- . Transient characteristics of C3H8/O2 turbulent mixing in a hypersonic pulse detonation engine. Proceedings of the 9th WSEAS International Conference on Applications of Computer Engineering, ACE '10 (2010). record
- . Direct thrust force measurement of pulse detonation engine. AIP Conference Proceedings (2012). doi:10.1063/1.4704344
- . Computations of shear driven vortex flow in a cylindrical cavity using a modified k-έ turbulence model. International Communications in Heat and Mass Transfer (2010). doi:10.1016/j.icheatmasstransfer.2010.06.021
- . Large Eddy Simulation of shear-driven vortex flow in a cylindrical cavity. International Conference on Theoretical and Applied Mechanics, International Conference on Fluid Mechanics and Heat and Mass Transfer - Proceedings (2010). record
- . Whirling flames for fuel economy and low NOx combustion. AIP Conference Proceedings (2010). doi:10.1063/1.3464845
- . Computational and experimental investigations of turbulent asymmetric vortex flames. International Communications in Heat and Mass Transfer (2011). doi:10.1016/j.icheatmasstransfer.2010.12.001
- . Large eddy simulation and preliminary modeling of the flow downstream a variable geometry swirler for gas turbine combustors. International Communications in Heat and Mass Transfer (2011). doi:10.1016/j.icheatmasstransfer.2011.05.017
- . Highly-resolved large eddy simulation of the nonreacting flow in an asymmetric vortex combustor. AIP Conference Proceedings (2012). doi:10.1063/1.4704242
- . Implementation of the eddy dissipation model of turbulent non-premixed combustion in OpenFOAM. International Communications in Heat and Mass Transfer (2011). doi:10.1016/j.icheatmasstransfer.2010.12.012
- . Comparison of eddy dissipation model and presumed probability density function model for temperature prediction in a non-premixed turbulent methane flame. AIP Conference Proceedings (2012). doi:10.1063/1.4704240
- . Integrating a simplified P-N radiation model with EdmFoam1.5: Model assessment and validation. International Communications in Heat and Mass Transfer (2012). doi:10.1016/j.icheatmasstransfer.2012.03.009
- . Performance of RANS turbulence models in predicting strained flows in a curved duct. International Conference on Theoretical and Applied Mechanics, International Conference on Fluid Mechanics and Heat and Mass Transfer - Proceedings (2010). record
- . Computational study of decaying annular vortex flow using the R ε/k-ε turbulence model. Applied Mathematical Modelling (2012). doi:10.1016/j.apm.2011.11.082
- . On rans modeling of unconfined swirl flow. CFD Letters (2014). record
- . Effects of hydrogen addition on the structure and pollutant emissions of a turbulent unconfined swirling flame. International Communications in Heat and Mass Transfer (2012). doi:10.1016/j.icheatmasstransfer.2012.03.020
- . Entropy generation in turbulent swirl-stabilized flame: Effect of hydrogen enrichment. Applied Mechanics and Materials (2013). doi:10.4028/www.scientific.net/AMM.388.280
- . Numerical simulation of entropy generation in hydrogen enriched swirl stabilized combustion. CFD Letters (2013). record
- . A perspective of the Malaysian highway energy consumption and future power supply. Energy Policy (2011). doi:10.1016/j.enpol.2011.03.034
- . Effects of buildings aspect ratio, wind speed and wind direction on flow structure and pollutant dispersion in symmetric street canyons: A review. International Journal of Mechanical and Materials Engineering (2012). record
- . A review on the flow structure and pollutant dispersion in urban street canyons for urban planning strategies. SIMULATION (2014). doi:10.1177/0037549714528046
- . Characteristics of biomass in flameless combustion: A review. Renewable and Sustainable Energy Reviews (2014). doi:10.1016/j.rser.2014.01.079
- . Effects of swirl intensity on heat transfer and entropy generation in turbulent decaying swirl flow. Applied Thermal Engineering (2014). doi:10.1016/j.applthermaleng.2014.05.059
- . Numerical simulations of the effect of an isotropic heat field on the entropy generation due to natural convection in a square cavity. Energy Conversion and Management (2014). doi:10.1016/j.enconman.2014.05.093
- . CFD modelling of entropy generation in turbulent pipe flow: Effects of temperature difference and swirl intensity. Applied Thermal Engineering (2016). doi:10.1016/j.applthermaleng.2016.02.014
- . Entropy generation due to viscous dissipation around a wells turbine blade: A preliminary numerical study. Energy Procedia (2014). doi:10.1016/j.egypro.2014.06.099
- . Performance analysis of wells turbine blades using the entropy generation minimization method. Renewable Energy (2016). doi:10.1016/j.renene.2015.09.045
- . Passive flow control for aerodynamic performance enhancement of airfoil with its application in Wells turbine – Under oscillating flow condition. Ocean Engineering (2017). doi:10.1016/j.oceaneng.2017.03.010
- . Wells turbine for wave energy conversion: a review. International Journal of Energy Research (2017). doi:10.1002/er.3583
- . On the role of surface roughness in the aerodynamic performance and energy conversion of horizontal wind turbine blades: a review. International Journal of Energy Research (2016). doi:10.1002/er.3580
- . Computational fluid dynamics study of dusty air flow over NACA 63415 airfoil for wind turbine applications. Jurnal Teknologi (2017). doi:10.11113/jt.v79.11877
- . Performance of a wind turbine blade in sandstorms using a CFD-BEM based neural network. Journal of Renewable and Sustainable Energy (2020). doi:10.1063/5.0012272
- . Numerical Study for a Marine Current Turbine Blade Performance under Varying Angle of Attack. Energy Procedia (2017). doi:10.1016/j.egypro.2017.07.143
- . Numerical simulation of the flow around a subsea pipeline with different protection methods. Proceedings of the Institution of Mechanical Engineers Part M: Journal of Engineering for the Maritime Environment (2017). doi:10.1177/1475090216632017
- . Experimental investigation of erosion-corrosion phenomena in a steel fitting due to plain and slurry seawater flow. International Journal of Mechanical and Materials Engineering (2014). doi:10.1186/s40712-014-0022-7
- . Optimum operational performance of a new stand-alone agricultural greenhouse with integrated-TPV solar panels. Solar Energy (2016). doi:10.1016/j.solener.2016.07.017
- . Exergy analysis of Garri “2” 180 MW combined cycle power plant. Renewable and Sustainable Energy Reviews (2017). doi:10.1016/j.rser.2017.05.077
- . Exergy analysis of large and impounded hydropower plants: Case study El Roseires Dam (280 MW). Environmental Progress and Sustainable Energy (2020). doi:10.1002/ep.13362
- . Acceleration of Computational Fluid Dynamics Simulations by Parallelization of the Linear Equation Solver Using Wavefront Technique. 26th International Conference on Computer Theory and Applications, ICCTA 2016 - Proceedings (2016). doi:10.1109/ICCTA40200.2016.9512940
- . Revisiting the lid-driven cavity flow problem: Review and new steady state benchmarking results using GPU accelerated code. Alexandria Engineering Journal (2017). doi:10.1016/j.aej.2016.09.013
- . Aerodynamics of a trapped vortex combustor: A comparative assessment of RANS based CFD models. Journal of Advanced Research in Fluid Mechanics and Thermal Sciences (2018). record
- . Evaluation criteria for a flameless combustor based on recirculation and mixing - A CFD approach. Acta Astronautica (2018). doi:10.1016/j.actaastro.2018.07.054
- . Improving indoor thermal comfort by using phase change materials: A review. International Journal of Energy Research (2018). doi:10.1002/er.4000
- . Numerical investigation of turbulent flow and heat transfer over partially open cavities effect of opening ratio. Thermal Science (2017). doi:10.2298/TSCI150309126A
- . Development of a novel control strategy for a multiple-circuit roof-top bus air-conditioning system in hot humid countries. International Journal of Mechanical and Materials Engineering (2007). record
- . Development of novel control strategy for multiple circuit, roof top bus air conditioning system in hot humid countries. Energy Conversion and Management (2008). doi:10.1016/j.enconman.2007.12.032
- . Thermal design of automobile exhaust based thermoelectric generators: Objectives and challenges. International Journal of Automotive Technology (2008). doi:10.1007/s12239-008-0020-y
- . Critical review of thermoelectrics in modern power generation applications. Thermal Science (2009). doi:10.2298/TSCI0903165S
- . Numerical study of the heat transfer augmentation in pipes with internal discontinous longetudinal fins. International Journal of Mechanical and Materials Engineering (2009). record
- . CFD analysis of incompressible turbulent swirling flow through Zanker plate. Engineering Applications of Computational Fluid Mechanics (2009). doi:10.1080/19942060.2009.11015291
- . CFD insight of the flow dynamics in a novel swirler for gas turbine combustors. International Communications in Heat and Mass Transfer (2009). doi:10.1016/j.icheatmasstransfer.2009.06.013
- . Augmentation of turbulence and mixing in gas turbine combustors by introducing unsteady effects. Proceedings of the 2010 International Conference on Mechanical, Industrial, and Manufacturing Technologies, MIMT 2010 (2010). doi:10.1115/1.859544.paper78
- . Numerical simulation of confined vortex flow using a modified k-ε turbulence model. CFD Letters (2009). record
- . Uncharacteristic phenomenon in the nonisothermal taylor-couette flow. 2009 International Conference on Signal Processing Systems, ICSPS 2009 (2009). doi:10.1109/ICSPS.2009.191
- . Can large eddy simulation (LES) predict laminar to turbulent flow transition?. International Journal of Mechanical and Materials Engineering (2009). record
- . Judicial Authority and Rhetorical Strategies in Egyptian Abortion Rulings: A Computational Forensic Analysis. International Journal for the Semiotics of Law (2025). doi:10.1007/s11196-025-10300-0
- . Innovation Fast Forward: Mining Human Ingenuity for Knowledge Capital. Independently published (2023). ASIN:B0CMK5QNW5; ISBN-13:979-8853630239
- . Self-debug Your Mind: It Takes Courage and AI. Independently published (2025). ASIN:B0F8NH9ZSS; ISBN-13:979-8283802404
- . AllMind Society. KNOWDYN (2025). ASIN:B0FPD6YWYZ
- . Kinetic Markets: Financial Mechanics of Liquidity, Volatility, and Risk. Independently published (2025). ASIN:B0GCVNS4QR; ISBN-13:979-8241480088
- . Adjoint Thinking: How to Think with Machines Without Losing Your Mind. Independently published (2026). ASIN:B0H3DWP3SP; ISBN-13:979-8199140843